Recombinant Plasmodium falciparum Erythrocyte-binding antigen 175, partial | CSB-EP325650PLR

Recombinant Plasmodium falciparum Erythrocyte-binding antigen 175, partial | CSB-EP325650PLR | Cusabio

Alternative Name(s): Erythrocyte-binding antigen 175; EBA-175

Gene Names: N/A

Research Areas: Others

Organism: Plasmodium falciparum (isolate Camp / Malaysia)

AA Sequence: GDDYCQDKTKMIETLKVECKEKPCEDDNCKSKCNSYKEWISKKKEEYNKQAKQYQEYQKGNNYKMYSEFKSIKPEVYLKKYSEKCSNLNFEDEFKEELHSDYKNKCTMCPEVKDVPISIIRNNEQTSQEAVPEENTEIAHRTETPSISEGPKGNEQKERDDDSLSKISVSPENSRPETDAKDTSNLLKLKGDVDISMPKA

Source: E.coli

Tag Info: N-terminal 10xHis-tagged

Expression Region: 634-833aa

Sequence Info: Partial

MW: 28.7 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Binds to host erythrocytes; may act as bridge between erythrocytes and merozoites.

Reference: "Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion." Sim B.K., Orlandi P.A., Haynes J.D., Klotz F.W., Carter J.M., Camus D., Zegans M.E., Chulay J.D. J. Cell Biol. 111:1877-1884(1990)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Binds to host erythrocytes; may act as bridge between erythrocytes and merozoites.

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P19214

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A