Cusabio Human Recombinants
Recombinant Human Heat shock protein beta-2 (HSPB2) | CSB-EP614956HU
- SKU:
- CSB-EP614956HU
- Availability:
- 13 - 23 Working Days
Description
Recombinant Human Heat shock protein beta-2 (HSPB2) | CSB-EP614956HU | Cusabio
Alternative Name(s): DMPK-binding protein
Gene Names: HSPB2
Research Areas: Signal Transduction
Organism: Homo sapiens (Human)
AA Sequence: MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGSRAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVEP
Source: E.coli
Tag Info: N-terminal GST-tagged
Expression Region: 1-182aa
Sequence Info: Full Length
MW: 47.2 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: May regulate the kinase DMPK.
Reference: "Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner." Iwaki A., Nagano T., Nakagawa M., Iwaki T., Fukumaki Y. Genomics 45:386-394(1997)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: May regulate the kinase DMPK.
Involvement in disease:
Subcellular Location: Cytoplasm, Nucleus
Protein Families: Small heat shock protein (HSP20) family
Tissue Specificity: Expressed preferentially in skeletal muscle and heart but not in the lens.
Paythway:
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q16082
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM