Recombinant Rat Galectin-3-binding protein (Lgals3bp) | CSB-EP012888RA

Recombinant Rat Galectin-3-binding protein (Lgals3bp) | CSB-EP012888RA | Cusabio

Alternative Name(s): Cyp-C-associated protein ;CyCAPLectin galactoside-binding soluble 3-binding protein;Mac-2-binding protein ;MAC2BP ;Mac-2 BPProtein 90K

Gene Names: Lgals3bp

Research Areas: Others

Organism: Rattus norvegicus (Rat)

AA Sequence: AKDGDMRLVNGASASEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALSRAAFGPGKGPIMLDEVECTGNESSLANCSSLGWMVSHCGHEKDAGVVCSNDSRGIHILDLSGELPDALGQIFDSQQDCDLFIQVTGQGHGDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQGYCGRLFVTLLPQDPTFHTPLELYEYAQATGDSVLEDLCVQFLAWNFEPLTQAEAWLSVPNALIQALLPKSELAVSSELDLLKAVDQWSTATGASHGDVERLVEQIRFPMMLPQELFELQFNLSLYQGHQALFQRKTMEALEFHTVPLKVLAKYRSLNLTEDVYKPRLYTSSTWSSLLMAGAWSTQSYKYRQFYTYNYGSQSRYSSYQNFQTPQHPSFLFKDKLISWSATYLPTIQSCWNYGFSCTSDELPVLGLTTSSYSDPTIGYENKALILCGGYSVVDVTTFIGSKAPIPGTQETNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDTE

Source: E.coli

Tag Info: N-terminal 6xHis-tagged

Expression Region: 19-574aa

Sequence Info: Full Length of Mature Protein

MW: 65.8 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells .

Reference: The 90K protein increases major histocompatibility complex class I expression and is regulated by hormones, gamma-interferon, and double-strand polynucleotides.Grassadonia A., Tinari N., Fiorentino B., Suzuki K., Nakazato M., De Tursi M., Giuliani C., Napolitano G., Singer D.S., Iacobelli S., Kohn L.D.Endocrinology 145:4728-4736(2004)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells (By similarity).

Involvement in disease:

Subcellular Location: Secreted, Secreted, extracellular space, extracellular matrix

Protein Families:

Tissue Specificity: Detected in thyroid (at protein level).

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: O70513

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A