Recombinant Neisseria meningitidis serogroup B Quinolinate synthase A (nadA) | CSB-EP878213NGG

Recombinant Neisseria meningitidis serogroup B Quinolinate synthase A (nadA) | CSB-EP878213NGG | Cusabio

Alternative Name(s): nadA; NMB0394; Quinolinate synthase A; EC 2.5.1.72

Gene Names: nadA

Research Areas: Others

Organism: Neisseria meningitidis serogroup B (strain MC58)

AA Sequence: MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLWQGSCIVHNEFKGQELAALKAEHPEAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKQFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKKKDVFNGMGPA

Source: E.coli

Tag Info: N-terminal 6xHis-tagged

Expression Region: 1-370aa

Sequence Info: Full Length

MW: 44.2 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.

Reference: "Expression of the meningococcal adhesin NadA is controlled by a transcriptional regulator of the MarR family." Schielke S., Huebner C., Spatz C., Nagele V., Ackermann N., Frosch M., Kurzai O., Schubert-Unkmeir A. Mol. Microbiol. 72:1054-1067(2009)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.

Involvement in disease:

Subcellular Location: Cytoplasm

Protein Families: Quinolinate synthase A family, Type 1 subfamily

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q9K105

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A