Recombinant Mouse Desert hedgehog protein (Dhh), partial (Active) | CSB-AP000541MO
- 5 to 10 Working Days
Recombinant Mouse Desert hedgehog protein (Dhh) ,partial (Active) | CSB-AP000541MO | Cusabio
Protein Description: Partial
Alternative Name (s) : DHH,
Gene Names: Dhh
Research Areas: Stem Cells
Species: Mus musculus (Mouse)
Tag Info: Tag-Free
Expression Region: 24-198aa
Sequence Info: IIGPGRGPVG RRRYVRKQLV PLLYKQFVPS MPERTLGASG PAEGRVTRGS ERFRDLVPNY NPDIIFKDEE NSGADRLMTE RCKERVNALA IAVMNMWPGV RLRVTEGWDE DGHHAQDSLH YEGRALDITT SDRDRNKYGL LARLAVEAGF DWVYYESRNH IHVSVKADNS LAVRAGG
Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by murine MC3T3E1 cells is 520 μg/ml.
MW: 20.0 kDa
Purity: >98% as determined by SDSPAGE and HPLC.
Endotoxin: Less than 1.0 EU/µg as determined by LAL method.
Relevance: Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
PubMed ID: 7916661; 7720571
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Function: Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
Involvement in disease:
Subcellular Location: Desert hedgehog protein N-product: Cell membrane, Lipid-anchor, Extracellular side, Note=The N-terminal peptide remains associated with the cell surface, SUBCELLULAR LOCATION: Desert hedgehog protein C-product: Secreted, extracellular space
Protein Families: Hedgehog family
Tissue Specificity: Expressed in adult testes. Not expressed in limb buds.
Form: Lyophilized powder
Buffer: Lyophilized from a 0.2 μm filtered PBS, pH 7.4,1 mM DTT, 0.05 % Tween-80
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q61488
Uniprot Entry Name: DHH_MOUSE
HGNC Database Link: N/A
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: N/A