Recombinant Human Neurotrophin-4 protein (NTF4) (Active) | CSB-AP002831HU

Recombinant Human Neurotrophin-4 protein (NTF4) (Active) | CSB-AP002831HU | Cusabio

Protein Description: Full Length of Mature Protein

Alternative Name (s) : NT-4, NT-5, Neutrophic factor 4

Gene Names: NTF4,NTF5

Research Areas: Neuroscience

Species: Homo sapiens (Human)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 81-210aa

Sequence Info: M+GVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg

MW: 14.1 kDa

Purity: >97% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Target-derived survival factor for peripheral sensory sympathetic neurons.

PubMed ID: 1742028; 1313578; 15489334; 10631974; 19765683; 20215012

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Target-derived survival factor for peripheral sensory sympathetic neurons.

Involvement in disease: Glaucoma 1, open angle, O (GLC1O)

Subcellular Location: Secreted

Protein Families: NGF-beta family

Tissue Specificity: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.

Paythway: MAPKsignalingpathway

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 5.5

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P34130

Uniprot Entry Name: NTF4_HUMAN

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM