Cusabio Human Recombinants
Recombinant Human Lipoyltransferase 1, mitochondrial (LIPT1) | CSB-EP896479HU
- SKU:
- CSB-EP896479HU
- Availability:
- 3 - 7 Working Days
Description
Recombinant Human Lipoyltransferase 1, mitochondrial (LIPT1) | CSB-EP896479HU | Cusabio
Alternative Name(s): Lipoate biosynthesis protein Lipoate-protein ligase Lipoyl ligase
Gene Names: LIPT1
Research Areas: Signal Transduction
Organism: Homo sapiens (Human)
AA Sequence: KTVKNGLILQSISNDVYQNLAVEDWIHDHMNLEGKPILFFWQNSPSVVIGRHQNPWQECNLNLMREEGIKLARRRSGGGTVYHDMGNINLTFFTTKKKYDRMENLKLIVRALNAVQPQLDVQATKRFDLLLDGQFKISGTASKIGRTTAYHHCTLLCSTDGTFLSSLLKSPYQGIRSNATASIPSLVKNLLEKDPTLTCEVLMNAVATEYAAYHQIDNHIHLINPTDETLFPGINSKAKELQTWEWIYGKTPKFSINTSFHVLYEQSHLEIKVFIDIKNGRIEICNIEAPDHWLPLEIRDKLNSSLIGSKFCPTETTMLTNILLRTCPQDHKLNSKWNILCEKIKGIM
Source: E.coli
Tag Info: N-terminal 6xHis-tagged
Expression Region: 26-373aa
Sequence Info: Full Length of Mature Protein
MW: 45.7 kDa
Purity: Greater than 85% as determined by SDS-PAGE.
Relevance: Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
Reference: "Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase." Soreze Y., Boutron A., Habarou F., Barnerias C., Nonnenmacher L., Delpech H., Mamoune A., Chretien D., Hubert L., Bole-Feysot C., Nitschke P., Correia I., Sardet C., Boddaert N., Hamel Y., Delahodde A., Ottolenghi C., de Lonlay P. Orphanet J. Rare Dis. 8:192-192(2013)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function:
Involvement in disease:
Subcellular Location:
Protein Families:
Tissue Specificity:
Paythway:
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q9Y234
HGNC Database Link: N/A
UniGene Database Link: N/A
KEGG Database Link: N/A
STRING Database Link: N/A
OMIM Database Link: N/A