Recombinant Human Interleukin-5 protein (IL5) (Active) | CSB-AP001721HU

Recombinant Human Interleukin-5 protein (IL5) (Active) | CSB-AP001721HU | Cusabio

Protein Description: Full Length of Mature Protein

Alternative Name (s) : IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF,

Gene Names: IL5

Research Areas: Immunology

Species: Homo sapiens (Human)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 20-134aa

Sequence Info: M+IPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of ＞ 1.0 × 107 IU/mg.

MW: 13.3 kDa

Purity: >98% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.

PubMed ID: 3024129; 2824500; 3498940; 2823259; 15489334; 2361960; 2037074; 8483502; 22153509

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: IL-5 family

Tissue Specificity:

Paythway: Jak-STATsignalingpathway

Form: Lyophilized powder

Buffer: Lyophilized from a a 0.2 µm filtered 20mM PB, pH 7.5, 3 % trehalose, 0.1 % Tween-80

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P05113

Uniprot Entry Name: IL5_HUMAN

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM