Recombinant Human Interleukin-5 (IL5) | CSB-YP011662HU

Recombinant Human Interleukin-5 (IL5) | CSB-YP011662HU | Cusabio

Alternative Name(s): B-cell differentiation factor I Eosinophil differentiation factor T-cell replacing factor Short name: TRF

Gene Names: IL5

Research Areas: Immunology

Organism: Homo sapiens (Human)

AA Sequence: IPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES

Source: Yeast

Tag Info: C-terminal 6xHis-tagged

Expression Region: 20-134aa

Sequence Info: Full Length of Mature Protein

MW: 15.1 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.

Reference: "Human interleukin-5 expressed in Escherichia coli: assignment of the disulfide bridges of the purified unglycosylated protein." Proudfoot A.E.I., Davies J.G., Turcatti G., Wingfield P.T. FEBS Lett. 283:61-64(1991)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: IL-5 family

Tissue Specificity:

Paythway: Jak-STATsignalingpathway

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P05113

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM