Recombinant Human Interleukin-17B protein (IL17B) (Active) | CSB-AP001651HU

Recombinant Human Interleukin-17B protein (IL17B) (Active) | CSB-AP001651HU | Cusabio

Protein Description: Full Length of Mature Protein

Alternative Name (s) : IL-17B, Interleukin-20, IL-20, Neuronal interleukin-17-related factor,

Gene Names: IL17B,IL20,NIRF,ZCYTO7,UNQ516/PRO1031

Research Areas: Immunology

Species: Homo sapiens (Human)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 21-180aa

Sequence Info: M+QPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inducing IL-8 secretion of human HepG2 cells is less than 1.0 μg/ml, corresponding to a specific activity of ＞ 1000 IU/mg.

MW: 18.3 kDa

Purity: >95% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.

PubMed ID: 10749887; 10639155; 12975309; 15489334

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: IL-17 family

Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Paythway: IL-17signalingpathway

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 7.4, with 0.1 % Tween-20 and 3 % Trehalose

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q9UHF5

Uniprot Entry Name: IL17B_HUMAN

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM