Recombinant Human Heme-binding protein 2 (HEBP2) | CSB-EP896539HU

Recombinant Human Heme-binding protein 2 (HEBP2) | CSB-EP896539HU | Cusabio

Alternative Name(s): Placental protein 23 ;PP23;Protein SOUL

Gene Names: HEBP2

Research Areas: Cell Biology

Organism: Homo sapiens (Human)

AA Sequence: AEPLQPDPGAAEDAAAQAVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKNEPTKENE

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 2-205aa

Sequence Info: Full Length of Mature Protein

MW: 38.7 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. Does not bind hin.

Reference: Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity.Liu L., McKeehan W.L.Genomics 79:124-136(2002)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.

Involvement in disease:

Subcellular Location: Cytoplasm, Mitochondrion

Protein Families: HEBP family

Tissue Specificity: Detected in placenta.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q9Y5Z4

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM