Cusabio Human Recombinants
Recombinant Human Heme-binding protein 2 (HEBP2) | CSB-EP896539HU
- 13 - 23 Working Days
Recombinant Human Heme-binding protein 2 (HEBP2) | CSB-EP896539HU | Cusabio
Alternative Name(s): Placental protein 23 ;PP23;Protein SOUL
Gene Names: HEBP2
Research Areas: Cell Biology
Organism: Homo sapiens (Human)
AA Sequence: AEPLQPDPGAAEDAAAQAVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKNEPTKENE
Tag Info: N-terminal 6xHis-SUMO-tagged
Expression Region: 2-205aa
Sequence Info: Full Length of Mature Protein
MW: 38.7 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. Does not bind hin.
Reference: Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity.Liu L., McKeehan W.L.Genomics 79:124-136(2002)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
Involvement in disease:
Subcellular Location: Cytoplasm, Mitochondrion
Protein Families: HEBP family
Tissue Specificity: Detected in placenta.
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q9Y5Z4
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM