Recombinant Human Granulocyte-macrophage colony-stimulating factor (CSF2) | CSB-YP006045HU
- 3 - 7 Working Days
Recombinant Human Granulocyte-macrophage colony-stimulating factor (CSF2) | CSB-YP006045HU | Cusabio
Alternative Name(s): Colony-stimulating factor Short name: CSF Molgramostin Sargramostim
Gene Names: CSF2
Research Areas: Immunology
Organism: Homo sapiens (Human)
AA Sequence: APARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE
Tag Info: N-terminal 6xHis-tagged
Expression Region: 18-144aa
Sequence Info: Full Length of Mature Protein
MW: 16.5 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Reference: "Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor."Cantrell M.A., Anderson D., Cerretti D.P., Price V., McKereghan K., Tushinski R.J., Mochizuki D.Y., Larsen A., Grabstein S., Gillis S., Cosman D.Proc. Natl. Acad. Sci. U.S.A. 82:6250-6254(1985)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Involvement in disease:
Subcellular Location: Secreted
Protein Families: GM-CSF family
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: P04141
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM