Recombinant Human Carbonic anhydrase 7 (CA7) (Active) | CSB-AP005411HU
- 5 to 10 Working Days
Recombinant Human Carbonic anhydrase 7 (CA7) (Active) | CSB-AP005411HU | Cusabio
Protein Description: Full Length
Alternative Name (s) : Carbonic Anhydrase 7; Carbonate Dehydratase VII; Carbonic Anhydrase VII; CA-VII; CA7
Gene Names: CA7
Research Areas: Cell Biology
Species: Homo sapiens (Human)
Tag Info: C-terminal 6xHis-tagged
Expression Region: 1-264aa
Sequence Info: MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
Biological Activity: The esterase activity is determined to be greater than 1000 pmol/min/ug
MW: 30.72 kDa
Purity: Greater than 95% as determined by SDS-PAGE.
Endotoxin: Less than 1.0 EU/µg as determined by LAL method.
Relevance: Carbonic Anhydrase 7 (CA7) is a member of the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Furthermore, Alpha-carbonic anhydrase is associated with many biological processes, including calcification, respiration, bone resorption, acid-base balance and the formation of aqueous humor. CA7 is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine, but it is inhibited coumarins, sulfonamide derivatives such as acetazolamide (AZA) by saccharin and Foscarnet.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Function: Reversible hydration of carbon dioxide.
Involvement in disease:
Subcellular Location: Cytoplasm
Protein Families: Alpha-carbonic anhydrase family
Buffer: 0.2 μm filtered 20 mM Tris-HCl, 150 mM NaCl, pH 8.0
Uniprot ID: P43166
Uniprot Entry Name:
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM