Recombinant Human Calmodulin-like protein 5 (CALML5) | CSB-EP973713HU
- 13 - 23 Working Days
Recombinant Human Calmodulin-like protein 5 (CALML5) | CSB-EP973713HU | Cusabio
Alternative Name(s): Calmodulin-like skin protein
Gene Names: CALML5
Research Areas: Cell Biology
Organism: Homo sapiens (Human)
AA Sequence: AGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTAAKKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQE
Tag Info: N-terminal 6xHis-SUMO-tagged
Expression Region: 2-146aa
Sequence Info: Full Length of Mature Protein
MW: 31.8 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Binds calcium. May be involved in terminal differentiation of keratinocytes.
Reference: Identification and cloning of a new calmodulin-like protein from human epidermis.Mehul B., Bernard D., Simonetti L., Bernard M.A., Schmidt R.J. Biol. Chem. 275:12841-12847(2000)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Binds calcium. May be involved in terminal differentiation of keratinocytes.
Involvement in disease:
Tissue Specificity: Particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation. Very low expression in lung.
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q9NZT1
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM