PTGS2 Antibody | CSB-RA920283A0HU
- 3 to 7 Working Days
PTGS2 Antibody | CSB-RA920283A0HU | Cusabio
PTGS2 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Antibody Type: Recombinant
Target Names: PTGS2
Aliases: Prostaglandin G/H synthase 2 (EC 22.214.171.124) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2), PTGS2, COX2
Background: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Isotype: Rabbit IgG
Clone Number: 10B2
Uniport ID: P35354
Modified: Cancer; Cardiovascular; Metabolism; Signal transduction
species: Homo sapiens (Human)
Species Reactivity: Human
Immunogen: A synthesized peptide derived from human COX2
Tested Applications: ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200
Purification Method: Affinity-chromatography
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.