N Antibody | CSB-PA318492LA01JAM
- 3 to 7 Working Days
N Antibody | CSB-PA318492LA01JAM | Cusabio
N Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: N
Aliases: Nucleoprotein (Nucleocapsid protein) (Protein N), N
Background: Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) . Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation (By similarity) . Interacts with host IKBKE (via Protein kinase domain) ; the interaction inhibits IKBKE kinase activity.
Uniport ID: P14239
Host Species: Rabbit
Species Reactivity: Junin mammarenavirus
Immunogen: Recombinant Junin mammarenavirus Nucleoprotein protein (1-564AA)
Immunogen Species: Junin mammarenavirus
Applications: ELISA, WB
Tested Applications: ELISA, WB; Recommended dilution: WB:1:500-1:5000
Purification Method: >95%, Protein G purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:5000
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others