Cusabio Monoclonal Antibodies
CD146 Monoclonal Antibody | CSB-MA013563A0m
- 3 to 7 Working Days
CD146 Monoclonal Antibody | CSB-MA013563A0m | Cusabio
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Product Type: Monoclonal Antibody
Target Name: CD146
Aliases: Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146) , MCAM, MUC18
Relevance: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Clone Number: 4D10C7
Uniport ID: P43121
Alternatives To SCBT: #N/A
Host Species: Mouse
Species Reactivity: Human
Immunogen: Recombinant Human Cell surface glycoprotein MUC18 protein (50-646AA)
Immunogen Species: Human
Applications: ELISA, WB, IF, FC
Tested Applications: ELISA, WB, IF, FC; Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200
Purification Method: >95%, Protein G purified
Dilution Ratio1: WB:1:500-1:2000
Dilution Ratio2: IF:1:50-1:200
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Immunology
Research Areas: Immunology