CD14 Monoclonal Antibody | CSB-MA0048791A0m

CD14 Monoclonal Antibody | CSB-MA0048791A0m | Cusabio

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Product Type: Monoclonal Antibody

Target Name: CD14

Aliases: CD14, CD14 molecule

Relevance: As a component of the innate immune system, the cell surface glycoprotein CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists as two forms, either anchored into the membrane by a GPI-anchor tail (mCD14) or present as a soluble form (sCD14) in normal serum and body fluids. CD14 was first described as a pattern recognition receptor for lipopolysaccharide (LPS) and a variety of ligands derived from different microbial sources, along with the co-receptors Toll-like receptor TLR 4 and MD-2. The binding of CD14 and LPS depends on the presence and catalytic activity of lipopolysaccharide-binding protein (LBP) . Besides its endotoxin signaling function, CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Multiple transcript variants resulting from alternative splicing encode the same isoform of CD14.

Isotype: IgG2b

Conjugate: Non-conjugated

Clone Number: 1A3B6

Uniport ID: P08571

Alternatives To SCBT: sc-58951/sc-19588/sc-7328/sc-52457/sc-1182

Host Species: Mouse

Species Reactivity: Human

Immunogen: Recombinant CD14 Protein

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;Recommended dilution:IHC:1:50-1:500

Purification Method: >95%, Protein G purified

Dilution Ratio1: IHC:1:50-1:500

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology;Stem cells