WTAP Antibody, HRP conjugated | CSB-PA618970LB01HU

WTAP Antibody, HRP conjugated | CSB-PA618970LB01HU | Cusabio

WTAP Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: WTAP

Aliases: Pre-mRNA-splicing regulator WTAP (Female-lethal (2) D homolog) (hFL (2) D) (WT1-associated protein) (Wilms tumor 1-associating protein), WTAP, KIAA0105

Background: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863) . Acts as a mRNA splicing regulator (PubMed:12444081) . Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532) . Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724) .

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q15007

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling