WSS1 Antibody, HRP conjugated | CSB-PA334485LB01SVG

WSS1 Antibody, HRP conjugated | CSB-PA334485LB01SVG | Cusabio

WSS1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: WSS1

Aliases: DNA-dependent metalloprotease WSS1 (EC 3.4.24.-) (DNA damage response protein WSS1) (SUMO-dependent isopeptidase WSS1) (Weak suppressor of SMT3 protein 1), WSS1

Background: Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. Involved in the repair of toxic DNA-protein cross-links (DPCs) such as covalently trapped topoisomerase 1 (TOP1) adducts on DNA lesions or DPCs induced by reactive compounds such as formaldehyde. Involved in DNA damage response and processing of stalled or collapsed replication forks by removing the covalently trapped TOP1 from chromatin. DPC proteolysis enables the repair of the lesions via downstream DNA repair pathways. May be recruited to DPCs via the SUMOylation of substrate proteins at damaged DNA sites.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: P38838

Host Species: Rabbit

Species Reactivity: Saccharomyces cerevisiae

Immunogen: Recombinant Saccharomyces cerevisiae DNA-dependent metalloprotease WSS1 protein (1-269AA)

Immunogen Species: Saccharomyces cerevisiae

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others