WDR77 Monoclonal Antibody | CSB-MA232183

WDR77 Monoclonal Antibody | CSB-MA232183 | Cusabio

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Product Type: Monoclonal Antibody

Target Name: WDR77

Aliases: 2610312E17Rik; Androgen receptor cofactor p44; C79984; HKMT1069; MEP 50; MEP-50; MEP50; MEP50_HUMAN; Methylosome protein 50; MGC2722; Nbla10071; p44; p44/Mep50; RGD1310479; RP11 552M11.3; WD repeat containing protein 77; WD repeat domain 77;

Relevance: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4) , methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

Isotype: IgG1

Conjugate: Non-conjugated

Clone Number:

Uniport ID: Q9BQA1

Alternatives To SCBT:

Host Species: Mouse

Species Reactivity: Human, Mouse, Rat

Immunogen: Purified recombinant human WDR77 protein fragments expressed in E.coli.

Immunogen Species: Human

Applications: ELISA, WB, ICC

Tested Applications: ELISA, WB, ICC;Recommended dilution:WB:1:500-1:5000, ICC:1:50-1:200

Purification Method: Affinity purified

Dilution Ratio1: WB:1:500-1:5000

Dilution Ratio2: ICC:1:50-1:200

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Buffer: Purified mouse monoclonal in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Epigenetics and Nuclear Signaling;Signal transduction