vpx Antibody, FITC conjugated | CSB-PA325553LC01HLU
- 3 to 7 Working Days
vpx Antibody, FITC conjugated | CSB-PA325553LC01HLU | Cusabio
vpx Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: vpx
Aliases: Protein Vpx (Viral protein X) (X ORF protein), vpx
Background: Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
Uniport ID: P18099
Host Species: Rabbit
Species Reactivity: Human immunodeficiency virus type 2 subtype A
Immunogen: Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx protein (1-113AA)
Immunogen Species: Human immunodeficiency virus type 2 subtype A
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others