VP35 Antibody, HRP conjugated | CSB-PA856262LB01RCT

VP35 Antibody, HRP conjugated | CSB-PA856262LB01RCT | Cusabio

VP35 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: VP35

Aliases: Polymerase cofactor VP35, VP35

Background: Acts as a polymerase cofactor in the RNA polymerase transcription and replication complex. Prevents establishment of cellular antiviral state by blocking virus-induced phosphorylation and activation of interferon regulatory factor 3 (IRF3), a transcription factor critical for the induction of interferons alpha and beta. This blockage is produced through the interaction with and inhibition host IKBKE and TBK1 producing a strong inhibition of the phosphorylation and activation of IRF3. Also inhibits the antiviral effect mediated by the interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2/PKR.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q91DE0

Host Species: Rabbit

Species Reactivity: Reston ebolavirus

Immunogen: Recombinant Reston ebolavirus Polymerase cofactor VP35 protein (1-329AA)

Immunogen Species: Reston ebolavirus

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others