Cusabio Polyclonal Antibodies
UCP3 Antibody | CSB-PA265027
- SKU:
- CSB-PA265027
- Availability:
- 3 to 7 Working Days
Description
UCP3 Antibody | CSB-PA265027 | Cusabio
UCP3 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: UCP3
Aliases: uncoupling protein 3 (mitochondrial, proton carrier)
Background: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP) . UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P55916
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide of human UCP3
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:2000-1:5000
Dilution Ratio2: IHC:1:25-1:100
Dilution Ratio3:
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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Neuroscience;Cancer;Cardiovascular;Metabolism;Signal transduction