Cusabio Polyclonal Antibodies
UBA1 Antibody, HRP conjugated | CSB-PA00149B0Rb
- SKU:
- CSB-PA00149B0Rb
- Availability:
- 3 to 7 Working Days
Description
UBA1 Antibody, HRP conjugated | CSB-PA00149B0Rb | Cusabio
UBA1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: UBA1
Aliases: Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1), UBA1, A1S9T UBE1
Background: Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system (PubMed:1606621, PubMed:1447181) . Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:1447181) . Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (PubMed:22456334) .
Isotype: IgG
Conjugate: HRP
Clonality: Polyclonal
Uniport ID: P22314
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Ubiquitin-like modifier-activating enzyme 1 protein (730-881AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Epigenetics & Nuclear Signaling;Cell biology