Cusabio Polyclonal Antibodies
TSEN54 Antibody | CSB-PA272793
- SKU:
- CSB-PA272793
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
TSEN54 Antibody | CSB-PA272793 | Cusabio
TSEN54 Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: TSEN54
Aliases: tRNA-splicing endonuclease subunit Sen54; tRNA-intron endonuclease Sen54; HsSen54; TSEN54; SEN54
Background: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2', 3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Zody M.C., Nature 440:1045-1049 (2006) .
Paushkin S.V., Cell 117:311-321 (2004) .
Ota T., Nat. Genet. 36:40-45 (2004) .
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q7Z6J9
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Synthesized peptide derived from internal of human TSEN54.
Immunogen Species: Human
Applications: ELISA, WB, IHC
Tested Applications: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100
Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:3000
Dilution Ratio3: IHC:1:50-1:100
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Epigenetics and Nuclear Signaling
Research Areas: Epigenetics & Nuclear Signaling