TPSB2 Antibody | CSB-PA030905
- 3 to 7 Working Days
TPSB2 Antibody | CSB-PA030905 | Cusabio
TPSB2 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: TPSB2
Aliases: tryptase beta 2 (gene/pseudogene)
Background: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Uniport ID: P20231
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Full length fusion protein
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:2000-1:5000
Dilution Ratio2: IHC:1:25-1:100
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others