TNFRSF1A Antibody | CSB-PA973584

TNFRSF1A Antibody | CSB-PA973584 | Cusabio

TNFRSF1A Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: TNFRSF1A

Aliases: CD120a; TBPI; TNF-RI; TNFAR; TNFR1

Background: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Jennifer Adjodha, AACR Meeting Abstracts, Apr 2006; 2006: 1028.
Kewu Huang, J Appl Physiol, Apr 2007; 102: 1632 - 1639.
Kiyoshi Asada, AACR Meeting Abstracts, Apr 2005; 2005: 202.
Elaine K Green, J. Med. Genet., Aug 2000; 37: 581.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P19438

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Synthesized peptide derived from Internal of human TNF receptor-1.

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;IHC:1:50-1:100

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:50-1:100

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cancer;Cardiovascular;Cell biology;Immunology;Signal transduction;Stem cells