Cusabio Polyclonal Antibodies
TIRAP Antibody | CSB-PA718808
- SKU:
- CSB-PA718808
- Availability:
- 3 to 7 Working Days
Description
TIRAP Antibody | CSB-PA718808 | Cusabio
TIRAP Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: TIRAP
Aliases: toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Background: The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P58753
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Full length fusion protein
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:2000-1:5000
Dilution Ratio2: IHC:1:25-1:100
Dilution Ratio3:
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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Immunology
Research Areas: Cardiovascular;Immunology;Signal transduction