TFAM Antibody | CSB-PA003208

TFAM Antibody | CSB-PA003208 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: TFAM

Aliases: RTEF1; TCF13L1; TEA domain family member 4; TEAD-4; TEAD4

Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.

Parisi M.A., Science 252:965-969 (1991) .
Tominaga K., Biochim. Biophys. Acta 1131:217-219 (1992) .
Fisher R.P., J. Biol. Chem. 267:3358-3367 (1992) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q00059

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from internal of human TFAM.

Immunogen Species: Human

Applications: ELISA, IHC, IF

Tested Applications: ELISA, IHC, IF;IHC:1:50-1:100, IF:1:100-1:500

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:50-1:100

Dilution Ratio3: IF:1:100-1:500

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Tags & Cell Markers

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Cardiovascular;Tags & Cell Markers;Metabolism;Signal transduction