Cusabio Polyclonal Antibodies
SUPT16H Antibody, HRP conjugated | CSB-PA835618LB01HU
- SKU:
- CSB-PA835618LB01HU
- Availability:
- 3 to 7 Working Days
Description
SUPT16H Antibody, HRP conjugated | CSB-PA835618LB01HU | Cusabio
SUPT16H Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: SUPT16H
Aliases: FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16), SUPT16H, FACT140 FACTP140
Background: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II) .
Isotype: IgG
Conjugate: HRP
Clonality: Polyclonal
Uniport ID: Q9Y5B9
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human FACT complex subunit SPT16 protein (187-282AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Epigenetics & Nuclear Signaling;Cell biology;Signal transduction