STAT6 Antibody | CSB-PA171110
- 3 to 7 Working Days
STAT6 Antibody | CSB-PA171110 | Cusabio
STAT6 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: STAT6
Aliases: signal transducer and activator of transcription 6, interleukin-4 induced
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Uniport ID: P42226
Host Species: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Fusion protein of human STAT6
Immunogen Species: Human
Applications: ELISA, WB
Tested Applications: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:2000-1:5000
Dilution Ratio2: WB:1:500-1:2000
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Epigenetics & Nuclear Signaling;Cancer;Signal transduction