SS18L1 Antibody | CSB-PA022701LA01HU

(No reviews yet) Write a Review
SKU:
CSB-PA022701LA01HU
Availability:
3 to 7 Working Days
  • SS18L1 Antibody
  • Western blot<br />
 All lanes: SS18L1 antibody at 2 µg/ml<br />
 Lane 1: Mouse kidney tissue<br />
 Lane 2: Mouse lung tissue<br />
 Lane 3: Mouse spleen tissue<br />
 Secondary<br />
 Goat polyclonal to rabbit IgG at 1/10000 dilution<br />
 Predicted band size: 43, 41, 34, 30, 44 kDa<br />
 Observed band size: 43 kDa<br />
  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA022701LA01HU at dilution of 1:100
  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA022701LA01HU at dilution of 1:100
€315.80 - €488.70

Description

SS18L1 Antibody | CSB-PA022701LA01HU | Cusabio

SS18L1 Antibody is Available at Gentaur Genprice with the fastest delivery.

Online Order Payment is possible or send quotation to info@gentaur.com.

Product Type: Polyclonal Antibody

Target Names: SS18L1

Aliases: Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1), SS18L1, CREST KIAA0693

Background: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: O75177

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Calcium-responsive transactivator protein (47-396AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:1000-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others

View AllClose

0 Reviews

View AllClose