Cusabio Polyclonal Antibodies
SRY Antibody | CSB-PA985423
- SKU:
- CSB-PA985423
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
SRY Antibody | CSB-PA985423 | Cusabio
SRY Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: SRY
Aliases: Delayed-early protein HRS; HRS; Pre-mRNA splicing factor SRP40; SFR5; SRP40
Background: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells By similarity. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons By similarity. Involved in different aspects of gene regulation including promoter activation or repression By similarity. Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
Sinclair A.H., Nature 346:240-244 (1990) .
Su H., Am. J. Hum. Genet. 52:24-38 (1993) .
Behlke M.A., Genomics 17:736-739 (1993) .
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q05066
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Synthesized peptide derived from internal of human SRY.
Immunogen Species: Human
Applications: ELISA, WB
Tested Applications: ELISA, WB;WB:1:500-1:3000
Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:3000
Dilution Ratio3:
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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Epigenetics and Nuclear Signaling
Research Areas: Epigenetics & Nuclear Signaling;Developmental biology