SQSTM1 Antibody, HRP conjugated | CSB-PA615696LB01HU

SQSTM1 Antibody, HRP conjugated | CSB-PA615696LB01HU | Cusabio

SQSTM1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: SQSTM1

Aliases: Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62), SQSTM1, ORCA OSIL

Background: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity) . May be involved in cell differentiation, apoptosis, immune response and regulation of K (+) channels.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q13501

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Sequestosome-1 protein (16-310AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Cardiovascular;Metabolism;Signal transduction