SPAG8 Antibody | CSB-PA858730LA01HU

SPAG8 Antibody | CSB-PA858730LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: SPAG8

Aliases: Sperm-associated antigen 8 (HSD-1) (Sperm membrane protein 1) (SMP-1) (Sperm membrane protein BS-84), SPAG8

Background: Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau (By similarity) . Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity) . Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis (PubMed:19548270) . May play a role in fertility and microtubule formation through interaction with RANBP9 (PubMed:10500252) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q99932

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Sperm-associated antigen 8 protein (236-409AA)

Immunogen Species: Human

Applications: ELISA, IF

Tested Applications: ELISA, IF; Recommended dilution: IF:1:50-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IF:1:50-1:200

Dilution Ratio3:

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cell biology;Stem cells