Cusabio Polyclonal Antibodies
SORL1 Antibody, HRP conjugated | CSB-PA821688LB01HU
- SKU:
- CSB-PA821688LB01HU
- Availability:
- 3 to 7 Working Days
Description
SORL1 Antibody, HRP conjugated | CSB-PA821688LB01HU | Cusabio
SORL1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: SORL1
Aliases: Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA), SORL1, C11orf32
Background: Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP) . Could play a role in cell-cell interaction. Involved in APP trafficking to and from the Golgi apparatus. It probably acts as a sorting receptor that protects APP from trafficking to late endosome and from processing into amyloid beta, thereby reducing the burden of amyloidogenic peptide formation. Involved in the regulation of smooth muscle cells migration, probably through PLAUR binding and decreased internalization.
Isotype: IgG
Conjugate: HRP
Clonality: Polyclonal
Uniport ID: Q92673
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Sortilin-related receptor protein (525-744AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Neuroscience
Research Areas: Neuroscience;Metabolism;Signal transduction