SNX17 Antibody, Biotin conjugated | CSB-PA614877LD01HU

SNX17 Antibody, Biotin conjugated | CSB-PA614877LD01HU | Cusabio

SNX17 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: SNX17

Aliases: Sorting nexin-17, SNX17, KIAA0064

Background: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns (3P) ) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q15036

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Sorting nexin-17 protein (280-457AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction