Cusabio Polyclonal Antibodies
SMAD7 Antibody | CSB-PA021793LA01HU
- SKU:
- CSB-PA021793LA01HU
- Availability:
- 3 to 7 Working Days
Description
SMAD7 Antibody | CSB-PA021793LA01HU | Cusabio
SMAD7 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: SMAD7
Aliases: Mothers against decapentaplegic homolog 7, MAD homolog 7, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 8, MAD homolog 8, Mothers against DPP homolog 8, SMAD family member 7, SMAD 7, Smad7, hSMAD7, SMAD7, MADH7, MADH8
Background: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: O15105
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Mothers against decapentaplegic homolog 7 protein (36-247AA)
Immunogen Species: Human
Applications: ELISA, WB, IF
Tested Applications: ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200
Purification Method: >95%, Protein G purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:5000
Dilution Ratio3: IF:1:20-1:200
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Epigenetics & Nuclear Signaling;Signal transduction