SLC11A1 Antibody | CSB-PA021380LA01HU

SLC11A1 Antibody | CSB-PA021380LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: SLC11A1

Aliases: Natural resistance-associated macrophage protein 1 (NRAMP 1) (Solute carrier family 11 member 1), SLC11A1, LSH NRAMP NRAMP1

Background: Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe (2+) and Mn (2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P49279

Host Species: Rabbit

Species Reactivity: Human, Rat

Immunogen: Recombinant Human Natural resistance-associated macrophage protein 1 protein (1-58AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF

Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:300, IF:1:50-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IHC:1:100-1:300

Dilution Ratio4: IF:1:50-1:200

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology;Metabolism;Signal transduction