SIRT3 Antibody | CSB-PA229200

SIRT3 Antibody | CSB-PA229200 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: SIRT3

Aliases: NAD-dependent deacetylase sirtuin-3; mitochondrial; SIR2-like protein 3; hSIRT3; SIRT3

Background: NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

Bechtel S., BMC Genomics 8:399-399 (2007) .
Schwer B., J. Cell Biol. 158:647-657 (2002) .
Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658 (2002) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9NTG7

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from C-terminal of human SIRT3.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Cardiovascular;Cell biology;Metabolism