SERPINE1 Antibody, HRP conjugated | CSB-PA11239B0Rb

SERPINE1 Antibody, HRP conjugated | CSB-PA11239B0Rb | Cusabio

SERPINE1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: SERPINE1

Aliases: Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1), SERPINE1, PAI1 PLANH1

Background: Serine protease inhibitor. Inhibits TMPRSS7 (PubMed:15853774) . Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU) . As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots (PubMed:8481516, PubMed:9207454, PubMed:17912461) . As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading (PubMed:9175705) . Acts as a regulator of cell migration, independently of its role as protease inhibitor (PubMed:15001579, PubMed:9168821) . It is required for stimulation of keratinocyte migration during cutaneous injury repair (PubMed:18386027) . It is involved in cellular and replicative senescence (PubMed:16862142) . Plays a role in alveolar type 2 cells senescence in the lung (By similarity) . Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (PubMed:25808697, PubMed:27046084) .

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: P05121

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Plasminogen activator inhibitor 1 protein (24-398AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cardiovascular

Research Areas: Cancer;Cardiovascular;Cell biology;Metabolism