SEPT2 Antibody, Biotin conjugated | CSB-PA617994LD01HU

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SKU:
CSB-PA617994LD01HU
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£252.64 - £390.96

Description

SEPT2 Antibody, Biotin conjugated | CSB-PA617994LD01HU | Cusabio

SEPT2 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: sept.2

Aliases: Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5), SEPT2, DIFF6 KIAA0158 NEDD5

Background: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q15019

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Septin-2 protein (1-361AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cell biology

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