RTN4RL2 Antibody | CSB-PA774805NA01HU

RTN4RL2 Antibody | CSB-PA774805NA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: RTN4RL2

Aliases: Reticulon-4 receptor-like 2 (Nogo receptor-like 3) (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2), RTN4RL2, NGRH1 NGRL3

Background: Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity) . Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (By similarity) . Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200) . Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q86UN3

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Peptide sequence from Human Reticulon-4 receptor-like 2 protein (355-372AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF

Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:1000-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4: IF:1:50-1:200

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience