Cusabio Polyclonal Antibodies
RPS27A Antibody, HRP conjugated | CSB-PA01639B0Rb
- SKU:
- CSB-PA01639B0Rb
- Availability:
- 3 to 7 Working Days
Description
RPS27A Antibody, HRP conjugated | CSB-PA01639B0Rb | Cusabio
RPS27A Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: RPS27A
Aliases: Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a (Small ribosomal subunit protein eS31) ], RPS27A, UBA80 UBCEP1
Background: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored) . When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains) . Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Isotype: IgG
Conjugate: HRP
Clonality: Polyclonal
Uniport ID: P62979
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Ubiquitin-40S ribosomal protein S27a protein (16-56AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Neuroscience
Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Cell biology