RPA1 Monoclonal Antibody | CSB-MA593248

RPA1 Monoclonal Antibody | CSB-MA593248 | Cusabio

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Product Type: Monoclonal Antibody

Target Name: RPA1

Aliases: Dmrpa1; Drosophila Replication Protein A; DRPA; HSSB; Human single stranded DNA binding protein; MST075; MSTP075; p70; REPA1; Replication factor A; Replication factor A protein 1; Replication protein A 70 kDa DNA-binding subunit;

Relevance: Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair.Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.Functions as component of the alternative replication protein A complex (aRPA) .aRPA binds single-stranded DNA and probably plays a role in DNA repair;it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC) , the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Isotype: IgG2a

Conjugate: Non-conjugated

Clone Number:

Uniport ID: P27694

Alternatives To SCBT:

Host Species: Mouse

Species Reactivity: Human, Monkey, Mouse, Rat

Immunogen: Purified recombinant human RPA70 protein fragments expressed in E.coli.

Immunogen Species: Human

Applications: ELISA, WB, ICC, IP

Tested Applications: ELISA, WB, ICC, IP;Recommended dilution:WB:1:500-1:5000, ICC:1:50-1:200IP:1:200-1:2000

Purification Method: Affinity purified

Dilution Ratio1: WB:1:500-1:5000

Dilution Ratio2: ICC:1:50-1:200

Dilution Ratio3: IP:1:200-1:2000

Dilution Ratio4:

Dilution Ratio5:

Buffer: Purified mouse monoclonal antibody in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics and Nuclear Signaling