ROBO1 Antibody, FITC conjugated | CSB-PA896760LC01HU

ROBO1 Antibody, FITC conjugated | CSB-PA896760LC01HU | Cusabio

ROBO1 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: ROBO1

Aliases: Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1), ROBO1, DUTT1

Background: Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development (PubMed:10102268, PubMed:24560577) . Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1 (PubMed:24560577) . In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity) . Plays a role in the regulation of cell migration via its interaction with MYO9B; inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257) . May be required for lung development (By similarity) .

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: Q9Y6N7

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Roundabout homolog 1 protein (29-143AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Cancer