RIPK3 Antibody, HRP conjugated | CSB-PA897497LB01HU

RIPK3 Antibody, HRP conjugated | CSB-PA897497LB01HU | Cusabio

RIPK3 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: RIPK3

Aliases: Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3), RIPK3, RIP3

Background: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q9Y572

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 protein (1-518AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cancer;Cell biology;Immunology;Signal transduction