RIPK3 Antibody | CSB-PA897497ESR1HU
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RIPK3 Antibody | CSB-PA897497ESR1HU | Cusabio
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Product Type: Polyclonal Antibody
Target Names: RIPK3
Aliases: Receptor-interacting serine/threonine-protein kinase 3 (EC 22.214.171.124) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3), RIPK3, RIP3
Background: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
Uniport ID: Q9Y572
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 protein (1-120AA)
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Purification Method: Antigen Affinity Purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: IHC:1:20-1:200
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Cancer;Cell biology;Immunology;Signal transduction